glutathione glutathione peroxidase Enzyme Molecule #1 Poster by Laguna Design / Science Photo Library Glutathione Peroxidase 2 - an

10.1073/pnas.1814775116

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Given the above, employing bioinformatics approaches, efforts were made in this study (a) to identify potential GPX and APX genes/proteins from 18 different plant species, (b) to analyze their exon/intron organization, (c) to provide detailed information about their physico-chemical properties, (d) to identify conserved motif signatures of GPX and APX, (e) to construct their phylogenetic trees and 3D models, (f) to generate protein-protein interaction networks, and finally (g) to analyze GPX and APX gene expression profiles

Aging significantly elevates ROS and inflammation that together exacerbate cardiometabolic and vascular diseases

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Additionally, it increases the expression of the peroxisome proliferator-activated receptor (PPAR) and phosphorylated form of AMP-activated protein kinase, improving the regulation of dyslipidemia and increasing lipid metabolism efficiency [130]