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Unraveling the regulation of hepatic metabolism by insulin

Exclusion criteria encompassed other neurological disorders, cerebral infarction caused by vertebral-basilar artery disease, cardioembolic stroke, or large-vessel vasculitis, acute or chronic infectious diseases, autoimmune or hematologic disorders, malignant tumors, mental abnormalities, severe heart, liver, or kidney dysfunction, intracerebral hemorrhage, and craniocerebral surgery history

Demir-Dora D, Ozsoy U, Yildirum Y, Yilmaz O, Aytac P, Yilmaz B, et al

For example, the activity of G6PD was significantly decreased in high-glucose-induced EC senescence, leading to decreased endothelial nitric oxide synthase (eNOS) activity and reduced antioxidant capacity 17

Both GST-activated nitrogen mustard (TLK286) and GT-activated arsenic-based (GSAO and Darinaparsin) prodrugs have displayed promising activities along with safe profiles

Co-corresponding author and co-first author Fabio Hecht, PhD, and co-first author Marco Zocchi, PhD, led the study in the Harris lab in the Department of Biomedical Genetics