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doi: 10.1371/journal.pone.0160291 47 KonoMYoshidaNMaedaKTsokosGC

GLOBAL GLUTATHIONE MARKET SIZE, BY CREAMS, BY GROUP, 2018-2032 (USD MILLION) TABLE 13

Aged skin has been linked to reduced barrier function, dryness, and a higher risk of skin illness [108]

Among the investigated compounds in the study, two compounds 3a and 3b, congeners (carbonyl reduction) of the pyridyl azachalcones were found to be potent enzyme inhibitors than kojic acid (IC 50 = 27.30 M) (Figure 5(a), 3a 3b )