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In testing the feasibility of applying trace element analysis of hair to accurately distinguish patients with prostate cancer from healthy individuals, Tan and Chen 49 demonstrated that trace element analysis of scalp hair, including nine elements (Zn, Cr, Mg, Ca, Al, P, Cd, Fe and Mo), achieved 98.2% accuracy

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in 2000 about the effects of acetyl-L-carnitine on plasma membrane and sperm motility in semen samples of 41 men before freezing-thawing revealed that acetyl-L-carnitine could not prevent cryodamage to the membrane or motility integrity in human spermatozoa of subfertile men (87)

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It has been hypothesised that stimulation of melanin production may be a protective reaction of the oral mucosa, associated with detoxification of polycyclic amines and benzopyrenes, thus being a side effect of tobacco use [30]