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denticola spent culture supernatants (SCSs) by removing bacterial cells and outer membrane vesicles (OMVs) through multi-step centrifugations, filtration, and ultracentrifugation (see Experimental Procedures for the detail)

If receiving cancer treatment, supplementing with Glutathione may cause drug interactions and allow cancer cells to be resistant to chemotherapy drugs, thus decreasing their effectiveness and increasing oxidative stress

Agents and Actions , 32(3-4), 351-358

Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S et al (2018) Oncogenic signaling pathways in the cancer genome atlas

Systemic deficiency of glutathione in cystic fibrosis

A 2024 trial found a cream with 5% alpha-arbutin and 2% kojic acid worked about as well as a prescription melasma cream but with fewer side effects