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Thomas, M

Various preclinical models have been created that are showing the impact of metabolism on brain function and in particular the role that impaired metabolism plays in the neurodegeneration processes

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Second messenger-regulated protein kinases in the brain: their functional role and the action of antidepressant drugs J Neurochem 2000

However, posthoc analysis of all of the fibrate trials show significant benefits in terms of reducing CVD events, when looking at the subgroup of patients with elevated triglycerides and low HDL-C and features of the metabolic syndrome or diabetes (670,671)

31 Beyond skin models, DHA has been shown to be cytotoxic to liver (HepG3), cardiac (Ac16), and bronchial epithelial (BEAS-2B) cells at concentrations as low as 1.5 mM to 7.5 mM