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Keywords: Metformin, Vitamin B 12 deficiency, Diabetes mellitus, Vitamin B12, Type 2 diabetes mellitus Core Tip: In the last 20 years, there was increasing evidence of the presence of vitamin B12 deficiency among metformin-treated diabetic patients

It dramatically increased CNS choline levels in vivo (in rats)

Post-surgical recovery is a separate but related category

For injury recovery, some practitioners recommend 250-500mcg twice daily, injected as close to the injury site as practical

Normal angiogenesis involves tightly regulated VEGF expression that increases during injury and decreases as healing completes

PubMed Thomas, M.K., Nikooienejad, A., Bray, R., Cui, X., Wilson, J., Duffin, K., et al
