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The copper coordination chemistry of GHK-Cu enables controlled cellular delivery of bioavailable copper while simultaneously modulating gene expression patterns, making it a unique multifunctional signaling complex rather than a simple metal chelator
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We find that drugs which inhibit generation of glutamate by the glutathione cycle elicit decreases in cytosolic glutamate and decreased miniature excitatory post synaptic potential (mEPSC) frequency
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