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It involves a C-to-T substitution at position 677, which changes an alanine to a valine in the enzymes catalytic domain

A deficiency in B12 can lead to fatigue, memory problems, and weakness

Healthcare providers should be aware of this potential adverse effect and perform a thorough drug review when a patient experiences an acneiform eruption, including reviewing drug and eruption onset

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The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: A review of literature
