glutathione transferase mechanism of action The role S-transferases in human disease pathogenesis and their current inhibitors Glutathione S-Transferases in Cancer

Gemtuzumab ozogamicin: Time to resurrect

Reported side effects include water retention, flushing, headache, tingling in the extremities, elevated IGF-1 levels, impaired glucose tolerance, and injection site reactions including pain and infection risk

Methods Purification of recombinant GRXs The open reading frames (ORFs) of ROXY9 and its variants, GRXC2, GRXC2-CSS and HsGRX1 were amplified from plasmids described before (ROXY9 62

Pros and Cons Pros: Effective for dark spots Safer than hydroquinone Cons: Limited effect on overall dullness Safety and Combination Safe for long-term use and can be combined with glutathione-based regimens

Ngian GS, Guymer EK, Littlejohn GO

Eijk et al