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In addition, L-carnitine can also be prepared by enzymatic conversion of -dehydrocarnitine, enzymatic hydrolysis of trans-croton betaine, and enzymatic hydroxylation of -butyl betaine

Meta-analysis was performed using fixed-effects or random-effect model according to I 2 statistic

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Gross CJ, Henderson LM, Savaiano DA

For most healthy adults, the clinical trials at common doses do not demonstrate clear, proven harms, but the TMAO question remains an area of active research