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among these individuals, lower serum 25-hydroxyvitamin D 3 concentrations have been associated with increased disease activity and relapse rates (108-110)
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A similar correlation between intestinal barrier function and fecal microbial alterations has also been shown in alcohol-dependent patients (149, 164)

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Moreover, oral supplementation with N-acetylcysteine (NAC) effectively attenuated Hg-induced cytotoxicity by reducing mercury accumulation and modulating the expression of these critical genes