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Rapamycin analogs reduce mTORC2 signaling and inhibit AKT activation in AML

This is especially true for large-scale purifications or when dealing with complex protein samples

doi: 10.3389/fmed.2023.1181572

A lower, but still significant three-fold increase in ALT also occurred in BT474

PMID: 83 TajimaKHosonumaMFunayamaEIsobeJBabaYMurayamaMet al

Glutamine in neoplastic cells: focus on the expression and roles of glutaminases
