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Our discovery of a binding site on FBXO22 that is different than that of BACH1, and potentially other native targets, further emphasizes that recruiting E3s via allosteric sites is possible

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Also, vanin-1 showed a positive correlation with several cardiovascular risk factors including waist circumference, BMI, and carotid intima-media thickness 8

Typically, CD47 can allow tumor cells to evade macrophage-mediated elimination

This contrasts with the reports discussed earlier that there is widespread use of ICS in COPD patients (up to 86%) and, thus, the data generated in this study may not be representative of the COPD population using ICS in normal clinical practice

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