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doi: 10.1016/j.envpol.2024.124764

PFAS have been shown to alter immune system function in ways that increase susceptibility to NHL: Reduction in B-Cell Function: A 2020 study in Frontiers in Immunology found that exposure to PFAS reduced the production and functionality of B cells, which are a critical component of the adaptive immune system

Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimers neuropathology and cognitive deficits

The rapid onset of acquired resistance is the primary barrier to their clinical application [277]

Incidence of lactic acidosis in metformin users

Further study is needed to characterize adduct profiles in patients receiving low doses of APAP with preexisting disease (e.g., liver disease) to better understand the potential application of this biomarker across a range of APAP exposures