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Weve known for over 20 years that large doses of carnitine given intravenously in people within hours of a heart attack may have an antiarrhythmic effect, presumably by facilitating glucose oxidation in the failing heart muscle

Acide amin majoritairement prsent dans le cerveau, le pancras, les muscles et le cur

C., Meng Y., Jia X., Miikeda A

Role of ROS and RNS Sources in Physiological and Pathological Conditions

Transmethylamine-N-Oxide is associated with diffuse cardiac fibrosis in people living with HIV

Given that isotope tracer studies show BB is clearly formed following oral l-carnitine ingestion, and similarly, isotope-labeled BB was readily converted into isotope-labeled TMA/TMAO following oral ingestion, we hypothesized that low overall plasma concentrations of gut microbiotaproduced BB in humans may be the result of microbial BB breakdown into TMA, predominantly occurring in the lower intestinal track (colon) distal to the absorption of most nutrients like l-carnitine and BB