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The risks of opioid use while on Suboxone is more related to chasing the high that Suboxone is blocking, taking the same opioid dosing after even brief periods of sobriety or in combination with other depressant drugs like benzodiazepines or alcohol

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Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors

[DOI] [PMC free article] [PubMed] [Google Scholar] 154.Yang Q., Falahati A., Khosh A., Mohammed H., Kang W., Corachn A., Bariani M.V., Boyer T.G., Al-Hendy A