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doi:10.3390/ph16040504 8

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Some authors have evaluated this condition as being responsible for as much as 24 missed-school days per year for these children, or 15% of their childhood time, with an estimated yearly cost of $170,355

Current integrated interventions for these psychological symptoms include psychotherapy (e.g., cognitive behavioral therapy), pharmacotherapy (e.g., antidepressants), neuromodulation techniques (e.g., transcranial magnetic stimulation), hyperbaric oxygen therapy, lifestyle modifications (e.g., exercise and sleep management), and social support and rehabilitation programs