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PMID 7340824
ZO-1 expression was already reduced compared to wild type in 2-week old Mdr2 / EHBDs
Patients were selected after treatment completion, introducing potential selection bias
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The major antigenic determinant recognized by these antibodies consists of a cysteinyl sulfhydryl group (on a peptide or protein) covalently bound ortho- to the hydroxyl group and meta- to the acetamide on 3-(cystein- S -yl) APAP (Potter et al
