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Collagen and matrix biology The first published paper documenting collagen synthesis stimulation by GHK-Cu appeared in 1988: fibroblast cultures increased collagen output when exposed to GHK-Cu at concentrations as low as 10 M, with peak activity around 1 nM (Maquart et al., FEBS Letters, 1988)

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doi: 10.1016/j.arr.2023.102125 [DOI] [PubMed] [Google Scholar] 171.Xu Y, Xiao W