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Further evidence for the augmenting effect of melatonin on the anticancer activity of conventional chemotherapy comes from studies of doxorubicin [163,164] and paclitaxel [165]

doi:10.1146/annurev.bi.52.070183.003431

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Whereas the metabolism of dopamine generates large amounts of hydrogen peroxide, hydrogen peroxide generates reactive oxygen radicals via auto-oxidation of dopamine

Proc Natl Acad Sci (2007) 104(47):187549