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8-OHdG can be excised from the DNA during repair mechanisms, thus being released in the blood stream and subsequently be excreted in the urine, patients-derived biofluids where it can be detected (Lunec et al., 2002)

Although many patients might in theory, be able to significantly recover from the primary mechanical injury of TBI given appropriate acute surgical interventions and supportive care, the detrimental consequences of secondary injury often lead to long term physical, cognitive, and emotional impairments that markedly reduce quality of life

Rustagi V, Gupta SRR, Talwar C, Singh A, Xiao ZZ, Jamwal R, Bala K, et al

This ensures the shots work well and are safe

doi: 10.1016/j.jfda.2019.01.002, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 210.Martami F, Togha M, Seifishahpar M, Ghorbani Z, Ansari H, Karimi T, et al