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Description
McDonald et al., 2009

Martelletti et al., 2018)
Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1

In research, it's often studied for its effects on inflammatory skin conditions, gut inflammation (like IBD), and even systemic inflammatory responses

It happens when the body lacks enough healthy red blood cells or hemoglobin to transport oxygen
By examining specific conditions, the mechanistic links between mast cell dysregulation and neuroautoimmunity come into sharper focus
