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Cells are sourced from rodents, nonhuman primates or humans via embryonic/fetal tissue collection, post-mortem isolation, iPS cells or direct lineage conversion, and maintained in adherent, suspension or bioreactor systems

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According to NICE guideline NG198 on acne management, first-line options include fixed-combination topical treatments such as adapalene with benzoyl peroxide or benzoyl peroxide with clindamycin
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