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Short chain acylcarnitines have attracted a lot of attention in the context of diabetes and insulin resistance, with acetylcarnitine playing again a central role as a master regulator of energy metabolism strategies

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Porphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis

This is also in line with a study in older 16 months old APOE-TR mice which found the same pattern of decreased LCAs and increased SCAs in E4s compared to E3s, particularly in males (Shang et al., 2020)

doi: 10.1111/iju.14663

DOI: 10.1196/annals.1320.003