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Thus, we identify 15LO1 pathway activity in vitro as a prime driver of lower intracellular reduced GSH levels and export of GSSG

Support the nervous system and brain function

The CNS is particularly vulnerable to oxidative damage due to its high oxygen consumption, abundance of polyunsaturated fatty acids, and relatively low levels of antioxidant enzymes [158]

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Some evidence suggest that GSH is critical for the recycling of antioxidants like vitamin C [32,33] and consequently, vitamin E [34], which is an important inhibitor of the lipid peroxidation

Cells (3 10 5 ) were then plated on six-well plates and infected with the viral supernatant in the presence of 4 g ml 1 polybrene