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doi: 10.1016/0006-2952(87)90638-1

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Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy

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Therefore, supplementation is a good idea

It not only rapidly produces ATP, but also provides abundant substrates for cellular anabolic metabolism, reduces ROS generation through the pentose phosphate pathway, and produces excessive lactate that acidifies the extracellular environment, thereby promoting the survival and invasion of cancer cells [34, 35]