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Matza LS, Stewart KD, Land LF, Patel H, Boye KS (2022) Exit interviews examining the patient experience in clinical trials of tirzepatide for treatment of type 2 diabetes

When IGF1R is suppressed by siRNA, mouse melanoma cells fail to induce ATM kinase activity after irradiation (Macaulay et al., 2001), suggesting that IGF1R plays a critical role in mediating ATM