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doi: 10.1111/j.1399-0004.2011.01673.x

The escalation schedule built into the clinical protocol reflects the tolerability profile of combined receptor activation

The injection can occur intramuscularly or subcutaneously

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For the forepaws, a maximum of 5 could be reached (max 10 for both), counting 1 for each toe (hence max possible of 4) and 1 for the paw (in the forepaw the pollex was not considered for scoring)

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