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Its multimodal mechanisms of action and excellent tolerability make it a promising candidate for adjunctive or standalone treatment in mood disorders

Furthermore, AKT may directly activate the nicotinamide adenine nucleotide kinase (NADK) responsible for the phosphorylation of NADH forming NADPH (Jeon et al., 2012

among the latter, in patients who were responsive (effective group) and non-responsive (ineffective group) after 2 weeks of treatment

The evidence for the CNS effects of insulin relative to hepatic glucose production have been provided mostly with animal studies

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