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In early trials demonstrated side effect profiles similar to those of the other vaccines, including pain at the injection site, fatigue, headache, and fever
26 Other possible mechanisms include improvements in mitochondrial function and a reduction of glutamate, an excitatory neurotransmitter, which is also a precursor to GSH

This suggests the impact of B12 on infection outcome is not likely through the direct utilization of B12 by C

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