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in Nature Medicine found that NNMT inhibition in white adipose tissue increased energy expenditure and reduced fat mass in animal models without altering food intake or physical activity (Kraus et al., Nature Medicine )

Maintenance therapy : Following the loading phase, 1 mg every two to three months for life in cases of pernicious anaemia or malabsorption

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Case Rep Neurol

Furthermore, in Kenya a local district survey in Embu ( n = 512) revealed that 40% of school-aged children in Kenya had vitamin B 12 deficiency