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Preclinical Safety Evaluation In preclinical studies, BPC 157 did not lead to any serious toxicity in tested animals, including: mice rats rabbits dogs These studies provide a strong foundation for understanding the safety profile of BPC 157, indicating that it is well-tolerated across different species

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Rectal glutathione delivery eliminates digestive tract and liver metabolism losses, providing 40-50% more bioavailability through rectal vasculature