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Another natural product, Gypenosides, also exhibits potent anticancer effects by targeting the PI3/AKT/mTOR pathway

doi: 10.1093/abbs/gmx085

doi: 10.1186/s13018-022-03295-y 71 LiuHKongLCaoDZhanXGaoXSunHet al
Response of tyrosine hydroxylase and GTP cyclohydrolase I gene expression to estrogen in the brain catecholaminergic regions varies with mode of administration

In addition, in an Alzheimer brain, bloodbrain barrier fragility is responsible for peripheral inflammation spreading to the brain, leading to cognitive and non-cognitive symptoms (Takeda et al

83 , 461S465S (2006)
