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NADPH is the major regulator of cellular redox potential and is crucial for the action of different antioxidant systems, including the maintenance of reduced glutathione pools 29,31,53 (Fig

Additionally, AMPK reduces the activity of mammalian target of rapamycin complex 1 (mTORC1), leading to the dephosphorylation of mTORC1 and the targeting of FOXK1, FOXK2, and transcription factor EB (TFEB)

10.1038/s41419-019-1543-z 103 MaW.WeiS.ZhangB.LiW

Moreover, BBB disruption-induced microenvironment dysregulation aggravates metabolic imbalance (191)

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, and Matsumoto K (1995)

R21AI126146 to MJC), the Global Lyme Alliance (AMG), and NIAID Intramural Research Program (AMG)
