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We recently showed that PHF3 SPOC specifically binds the C-terminal domain (CTD) of the RNA polymerase II (Pol II) subunit RPB1 phosphorylated on serine-2 in tandem repeats 5

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That means using it is not just an unproven gamble on a supplement with limited evidence for competitive athletes, it is also a potential anti-doping violation

Synergistic Protocols & Adjuncts Triple-Support Regimen Morning: PQQ 20 mg + CoQ10 (ubiquinol) 100 mg Midday: ALA 300 mg Evening: CoQ10 100 mg + ALA 300 mg Lifestyle Synergies Exercise: Endurance and resistance training upregulate PGC-1, amplifying PQQs biogenic effects

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Funding This study was funded by grants MC-A656-5QD30 from the Medical Research Council-UK, 666 from the Maudsley Charity 094849/Z/10/Z from the Brain and Behavior Research Foundation, and Wellcome Trust to ODH