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Interestingly, the deletion of NOX2 following mouse TBI (Wang et al., 2018) or PTZ-induced SE ( 2 and resulting increased steady-state H 2 O 2 levels is necessary for NF-KB activation in macrophages (Li et al., 2018) and for microglia proliferation (Mander et al., 2006)

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In Marfan mice, NOX4 deficiency results in delayed aortic aneurysm progression and normalization of endothelial dysfunction in Marfan aorta (89)

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