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Most experts suggest a range of 20 to 40 mg per kilogram of body weight

Indeed, nanocarriers such as liposomes, polymeric micelles, metallic nanoparticles, or dendrimers all contribute to co-delivering different chemotherapeutics, and may represent an interesting strategy to increase the drug selectivity, diminish the onset of undesired side effects and, last but not least, overcome the resistance in cancer [118,119]

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Limitations and open questions Translational pharmacokinetics and receptor occupancy relationships are early

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