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This case does not establish that alkaline water is directly nephrotoxic in healthy individuals, but it highlights that absorbable alkali and mineral content may become clinically significant in vulnerable patients, especially those with reduced glomerular filtration rate, impaired renal excretion, or concurrent calcium-based medications

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Tetreault NA, Hakeem AY, Jiang S, Williams BA, Allman E, Wold BJ, Allman JM (2012) Microglia in the cerebral cortex in autism

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