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Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

doi: 10.1016/j.ebiom.2022.104055 15 Romero-FigueroaMDSRamrez-DurnNMontiel-JarqunJHorta-BaasG

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(2022) introduced naringenin-O-carbamate derivatives such as compound 3c, which showed potent inhibition of A aggregation, robust neuroprotection, and the ability to disaggregate Cu 2+ -induced A142 aggregates, a common pathway associated with metal ion dysregulation in AD brains

Large-scale, carefully planned randomized controlled trials (RCTs) that assess the safety and effectiveness of dietary interventions for PCOS are in dire need
