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Calcium plays an essential role in numerous physiological processes, such as neuronal excitability, synaptic plasticity, muscle contraction, and intracellular signaling [180]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Tartt A.N., Mariani M.B., Hen R., et al

DSIP is a natural sleep-promoting nonapeptide with a few beneficial functions

Its intracellular domain is associated with p120, b-catenin, and a-catenin, forming a complex that is bound to actin filaments (134)

On the other hand, Treg cells are adapted to lipid peroxide-enriched TME, and tumoral PMN-MDSC release oxygenated lipids to limit T cell activity to promote tumor growth
