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Description
The resistance of cytokines to chemotherapy, immunotherapy, and oncoprotein-targeted medications continues to be the major challenge in oncology, impacting PCa patients capability to get successful therapy over a lengthy period [236, 250, 251]
PMID: 25690343

Serine 615 phosphorylation enhances eNOS activity, working cooperatively with Ser1177 to enhance the binding affinity of the Ca 2 -CaM complex to eNOS, a critical step for eNOS activation, which ensures a robust response to Ca 2 signals (Tran et al., 2009

Berlin/Heidelberg, Germany: 2002

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doi: 10.1242/jcs.018093
