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On neutral trials, subjects are not required to respond

During RNA virus infection, mitofusin-2 interacts with NLRP3 to activate inflammasomes (57)

Apart from acne, underlying conditions such as skin infections or rosacea could also cause inflammation of the skin

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MtDNA damage results in impaired ETC function, reduced ATP generation, increased levels of ROS and disrupted calcium homeostasis, leading to exacerbated amyloid- (A) processing and aggregation in AD mice (47)

PPAR coactivator-1 (PGC-1) acts as a key factor and connects several regulatory cascades involved in the control of mitochondrial metabolism