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53 African populations demonstrate unique genetic advantages through higher frequencies of BCL2 protective variants promoting melanocyte survival, distinct ASIP gene polymorphisms affecting melanin production, and population-specific KIT ligand variants influencing MSCs maintenance

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Second, the role of metabolic reprogramming in ferroptosis highlights how sustained mechanical stress and inflammation reshape lipid, amino acid, iron, and glucose metabolic pathways in OA chondrocytes and synovial cells

Thus NADPH fuels the removal of H 2 O 2 by the glutathione system (65)

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10.1007/s10815-020-01909-0 61 IriawatiI.VitasastiS.RahmadianF