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We observed no significant effect of met4 and gcn4 mutations on GFP-Atg8 expression and GFP-Atg8 processing compared to the WT strain, suggesting that Met4 role in autophagy regulation under starvation does not extend to other nutrients besides sulfur

Reduced folic acid intake is associated with hyperhomocysteinemia

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The human leptin mutants K33A/Q34A/K35A (KQK-AAA) and S117N displayed partial agonism of human LepR, with maximal STAT3 responses of approximately 75% and 45% of WT leptin, respectively (Fig