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Toutefois, il est important de noter que les injections de B12 peuvent avoir des effets secondaires, bien que ces derniers soient gnralement rares

[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin
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[7] [8] Whilst B12 deficiency can cause serious health problems, supplementation is generally well-tolerated by most individuals

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Sterile Drug Products Produced by Aseptic Processing Current Good Manufacturing Practice Guidance for Industry