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Introduction This guideline is the third revised edition of the Thyroid Tumor Management Guidelines published in 2010 by the Japan Association of Endocrine Surgery (JAES) and the Japanese Society of Thyroid Surgery, and the Thyroid Tumor Management Guidelines 2018 published in 2018

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And it is related to cholesterol metabolism genes such as LXR, ATP-binding cassette transporter A1 (ABCA1), ATP-binding cassette G1 (ABCG1), acyl-coenzyme A oxidase 1 (ACOX1), apolipoprotein AI (apo AI) (Fig

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