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Furthermore, one study found that Ketamine inhibit the expression of GPX4 by attenuating KAT5 on the promoter region of GPX4, repressing the enrichment of histone H3 lysine 27 acetylation and RNA polymerase II (Li H

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Sensitivities of nociceptive neurons to heat stimulation and TRPV1 activation were increased by the activation of PKC and inflammatory mediators (Khasar et al., 1999