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Archived from the original on 25 April 2022

Brecka favours the secretagogue route on the grounds that it is less likely to shut down endogenous production

Differential effects of in vitro zinc treatment on gene expression in peripheral blood mononuclear cells derived from young and elderly individuals

Quasi-closed system A system is closed if there is no interaction with the external environment

Not all secretagogues are created equal, and their side effect profiles can differ dramatically

This is crucial because neuron signalling in the brain relies on electrical signals and fine chemical signals, which require a precisely regulated microenvironment, and this can be easily disturbed by molecules coming in from the blood