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Early-phase results or protocol publications [73] indicate that this study is actively enrolling patients and will provide valuable head-to-head data

The study included patients with episodic migraine (baseline of 6-9 days per month)

L-carnitine plays a key role in regulating acyl-CoA and acetyl-CoA and in maintaining free CoA levels within mitochondria, which is essential for maintaining metabolic flexibility (Figure 1) (18)

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Additionally, this paper also summarized a variety of measures to intervene in related diseases by targeting the reduction of TMAO levels, including probiotics, prebiotics, antibiotics, anti-inflammatory drugs, antiplatelet agents, hypoglycemic agents, lipid-lowering drugs, Chinese herbal monomers, herbal extracts, and formulas